A comparison of intrauterine hemopoietic cell transplantation and lentiviral gene transfer for the correction of severe β-thalassemia in a HbbTh3/+ murine model

Major hemoglobinopathies place tremendous strain on global resources. Intrauterine hemopoietic cell transplantation (IUHCT) and gene transfer (IUGT) can potentially reduce perinatal morbidities with greater efficacy than postnatal therapy alone. We performed both procedures in the thalassemic HbbTh3...

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Detalles Bibliográficos
Autores principales: Dighe, Niraja M., Tan, Kang Wei, Tan, Lay Geok, Shaw, Steven S.W., Buckley, Suzanne M.K., Sandikin, Dedy, Johana, Nuryanti, Tan, Yi-Wan, Biswas, Arijit, Choolani, Mahesh, Waddington, Simon N., Antoniou, Michael N., Chan, Jerry K.Y., Mattar, Citra N.Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Inc 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965454/
https://www.ncbi.nlm.nih.gov/pubmed/29605545
http://dx.doi.org/10.1016/j.exphem.2018.03.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965454/
https://www.ncbi.nlm.nih.gov/pubmed/29605545
http://dx.doi.org/10.1016/j.exphem.2018.03.006

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