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A feasibility study of colorectal cancer diagnosis via circulating tumor DNA derived CNV detection

Circulating tumor DNA (ctDNA) has shown great promise as a biomarker for early detection of cancer. However, due to the low abundance of ctDNA, especially at early stages, it is hard to detect at high accuracies while keeping sequencing costs low. Here we present a pilot stage study to detect large...

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Detalles Bibliográficos
Autores principales: Molparia, Bhuvan, Oliveira, Glenn, Wagner, Jennifer L., Spencer, Emily G., Torkamani, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965833/
https://www.ncbi.nlm.nih.gov/pubmed/29791457
http://dx.doi.org/10.1371/journal.pone.0196826