Perturbation of the metabolic network in Salmonella enterica reveals cross-talk between coenzyme A and thiamine pathways

Microorganisms respond to a variety of metabolic perturbations by repurposing or recruiting pathways to reroute metabolic flux and overcome the perturbation. Elimination of the 2-dehydropantoate 2-reductase, PanE, both reduces total coenzyme A (CoA) levels and causes a conditional HMP-P auxotrophy i...

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Detalles Bibliográficos
Autores principales: Ernst, Dustin C., Borchert, Andrew J., Downs, Diana M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965847/
https://www.ncbi.nlm.nih.gov/pubmed/29791499
http://dx.doi.org/10.1371/journal.pone.0197703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965847/
https://www.ncbi.nlm.nih.gov/pubmed/29791499
http://dx.doi.org/10.1371/journal.pone.0197703

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