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Perturbation of the metabolic network in Salmonella enterica reveals cross-talk between coenzyme A and thiamine pathways
Microorganisms respond to a variety of metabolic perturbations by repurposing or recruiting pathways to reroute metabolic flux and overcome the perturbation. Elimination of the 2-dehydropantoate 2-reductase, PanE, both reduces total coenzyme A (CoA) levels and causes a conditional HMP-P auxotrophy i...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965847/ https://www.ncbi.nlm.nih.gov/pubmed/29791499 http://dx.doi.org/10.1371/journal.pone.0197703 |