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Low shear stress upregulates the expression of fractalkine through the activation of mitogen-activated protein kinases in endothelial cells

Fractalkine (FKN) is a cytokine which plays an important role in atherosclerosis and other inflammatory diseases. Studies have shown that FKN induces integrin-independent leukocyte adhesion to primary endothelial cells under physiological flow conditions. Further, increased expression of FKN has bee...

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Detalles Bibliográficos
Autores principales: Ruze, Amanguli, Zhao, Yiwei, Li, Hui, Gulireba, Xiayimaidan, Li, Jing, Lei, Dongyu, Dai, Hongyan, Wu, Jiang, Zhao, Xin, Nie, Yongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams And Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965924/
https://www.ncbi.nlm.nih.gov/pubmed/29406386
http://dx.doi.org/10.1097/MBC.0000000000000701