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Low shear stress upregulates the expression of fractalkine through the activation of mitogen-activated protein kinases in endothelial cells
Fractalkine (FKN) is a cytokine which plays an important role in atherosclerosis and other inflammatory diseases. Studies have shown that FKN induces integrin-independent leukocyte adhesion to primary endothelial cells under physiological flow conditions. Further, increased expression of FKN has bee...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams And Wilkins
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965924/ https://www.ncbi.nlm.nih.gov/pubmed/29406386 http://dx.doi.org/10.1097/MBC.0000000000000701 |