Aquaporin-4 facilitator TGN-073 promotes interstitial fluid circulation within the blood–brain barrier: [(17)O]H(2)O JJVCPE MRI study

The blood–brain barrier (BBB), which imposes significant water permeability restriction, effectively isolates the brain from the systemic circulation. Seemingly paradoxical, the abundance of aquaporin-4 (AQP-4) on the inside of the BBB strongly indicates the presence of unique water dynamics essenti...

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Detalles Bibliográficos
Autores principales: Huber, Vincent J., Igarashi, Hironaka, Ueki, Satoshi, Kwee, Ingrid L., Nakada, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Cellular, Molecular and Developmental Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965936/
https://www.ncbi.nlm.nih.gov/pubmed/29481527
http://dx.doi.org/10.1097/WNR.0000000000000990

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965936/
https://www.ncbi.nlm.nih.gov/pubmed/29481527
http://dx.doi.org/10.1097/WNR.0000000000000990

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