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Additive analgesic effect of dexmedetomidine and dezocine administered intrathecally in a mouse pain model
BACKGROUND: It is known that dexmedetomidine can reduce opioid requirements and that there is a synergistic effect when dexmedetomidine and morphine (a full mu opioid receptor agonist) are administered together. However, it was unclear whether a synergistic or additive effect would be observed when...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966251/ https://www.ncbi.nlm.nih.gov/pubmed/29849948 http://dx.doi.org/10.18632/oncotarget.25304 |