UniPR1331, a small molecule targeting Eph/ephrin interaction, prolongs survival in glioblastoma and potentiates the effect of antiangiogenic therapy in mice

Glioblastoma multiforme (GBM) is the most malignant brain tumor, showing high resistance to standard therapeutic approaches that combine surgery, radiotherapy, and chemotherapy. As opposed to healthy tissues, EphA2 has been found highly expressed in specimens of glioblastoma, and increased expressio...

Descripción completa

Detalles Bibliográficos
Autores principales: Festuccia, Claudio, Gravina, Giovanni Luca, Giorgio, Carmine, Mancini, Andrea, Pellegrini, Cristina, Colapietro, Alessandro, Delle Monache, Simona, Maturo, Maria Giovanna, Sferra, Roberta, Chiodelli, Paola, Rusnati, Marco, Cantoni, Annamaria, Castelli, Riccardo, Vacondio, Federica, Lodola, Alessio, Tognolini, Massimiliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966254/
https://www.ncbi.nlm.nih.gov/pubmed/29849945
http://dx.doi.org/10.18632/oncotarget.25272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966254/
https://www.ncbi.nlm.nih.gov/pubmed/29849945
http://dx.doi.org/10.18632/oncotarget.25272

Ejemplares similares