HX-1171 attenuates pancreatic β-cell apoptosis and hyperglycemia-mediated oxidative stress via Nrf2 activation in streptozotocin-induced diabetic model

Streptozotocin (STZ) acts specifically on pancreatic beta cells, inducing cell destruction and cell dysfunction, resulting in diabetes. Many studies have reported that nuclear factor-erythroid 2-related factor 2 (Nrf2), a main regulator of antioxidant expression, prevents and improves diabetes-relat...

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Detalles Bibliográficos
Autores principales: Kim, Jimin, Shin, Su-Hyun, Kang, Jong-Koo, Kim, Jae Wha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966269/
https://www.ncbi.nlm.nih.gov/pubmed/29849938
http://dx.doi.org/10.18632/oncotarget.24916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966269/
https://www.ncbi.nlm.nih.gov/pubmed/29849938
http://dx.doi.org/10.18632/oncotarget.24916

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