Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels

ATP-sensitive potassium channels (K(ATP)) are energy sensors on the plasma membrane. By sensing the intracellular ADP/ATP ratio of β-cells, pancreatic K(ATP) channels control insulin release and regulate metabolism at the whole body level. They are implicated in many metabolic disorders and diseases...

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Detalles Bibliográficos
Autores principales: Wu, Jing-Xiang, Ding, Dian, Wang, Mengmeng, Kang, Yunlu, Zeng, Xin, Chen, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966361/
https://www.ncbi.nlm.nih.gov/pubmed/29594720
http://dx.doi.org/10.1007/s13238-018-0530-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966361/
https://www.ncbi.nlm.nih.gov/pubmed/29594720
http://dx.doi.org/10.1007/s13238-018-0530-y

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