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Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels

ATP-sensitive potassium channels (K(ATP)) are energy sensors on the plasma membrane. By sensing the intracellular ADP/ATP ratio of β-cells, pancreatic K(ATP) channels control insulin release and regulate metabolism at the whole body level. They are implicated in many metabolic disorders and diseases...

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Detalles Bibliográficos
Autores principales:	Wu, Jing-Xiang, Ding, Dian, Wang, Mengmeng, Kang, Yunlu, Zeng, Xin, Chen, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Higher Education Press 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966361/ https://www.ncbi.nlm.nih.gov/pubmed/29594720 http://dx.doi.org/10.1007/s13238-018-0530-y

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