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Simulated microgravity attenuates myogenic differentiation via epigenetic regulations

The molecular mechanisms involved in myogenic differentiation are relatively well-known. Myogenic differentiation is regulated by the sequential activation of the basic helix-loop-helix myogenic regulatory transcription factors (MRFs), and biomechanical signals play an important role in the regulati...

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Detalles Bibliográficos
Autores principales: Furukawa, Takuma, Tanimoto, Keiji, Fukazawa, Takahiro, Imura, Takeshi, Kawahara, Yumi, Yuge, Louis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966377/
https://www.ncbi.nlm.nih.gov/pubmed/29845109
http://dx.doi.org/10.1038/s41526-018-0045-0