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Distinct roles of XPF-ERCC1 and Rad1-Rad10-Saw1 in replication-coupled and uncoupled inter-strand crosslink repair

Yeast Rad1–Rad10 (XPF–ERCC1 in mammals) incises UV, oxidation, and cross-linking agent-induced DNA lesions, and contributes to multiple DNA repair pathways. To determine how Rad1–Rad10 catalyzes inter-strand crosslink repair (ICLR), we examined sensitivity to ICLs from yeast deleted for SAW1 and SLX...

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Detalles Bibliográficos
Autores principales: Seol, Ja-Hwan, Holland, Cory, Li, Xiaolei, Kim, Christopher, Li, Fuyang, Medina-Rivera, Melisa, Eichmiller, Robin, Gallardo, Ignacio F., Finkelstein, Ilya J., Hasty, Paul, Shim, Eun Yong, Surtees, Jennifer A., Lee, Sang Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966407/
https://www.ncbi.nlm.nih.gov/pubmed/29795289
http://dx.doi.org/10.1038/s41467-018-04327-0