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Cordycepin induces apoptosis of human ovarian cancer cells by inhibiting CCL5-mediated Akt/NF-κB signaling pathway

The chemokine, CCL5, is a key mediator for the recruitment of immune cells into tumors and tissues. Akt/NF-κB signaling is significantly activated by CCL5. However, the role of NF-κB inactivation in apoptosis induced by negative regulation of CCL5 remains unclear. Here, we analyzed the effect of cor...

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Detalles Bibliográficos
Autores principales: Cui, Zhen Yang, Park, Soo Jung, Jo, Eunbi, Hwang, In-Hu, Lee, Kyung-Bok, Kim, Sung-Woo, Kim, Dae Joon, Joo, Jong Chun, Hong, Seok Hoon, Lee, Min-Goo, Jang, Ik-Soon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966410/
https://www.ncbi.nlm.nih.gov/pubmed/29844932
http://dx.doi.org/10.1038/s41420-018-0063-4