Postnatal DNA demethylation and its role in tissue maturation

Development in mammals is accompanied by specific de novo and demethylation events that are thought to stabilize differentiated cell phenotypes. We demonstrate that a large percentage of the tissue-specific methylation pattern is generated postnatally. Demethylation in the liver is observed in thous...

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Detalles Bibliográficos
Autores principales: Reizel, Yitzhak, Sabag, Ofra, Skversky, Yael, Spiro, Adam, Steinberg, Benjamin, Bernstein, Diana, Wang, Amber, Kieckhaefer, Julia, Li, Catherine, Pikarsky, Eli, Levin-Klein, Rena, Goren, Alon, Rajewsky, Klaus, Kaestner, Klaus H., Cedar, Howard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966414/
https://www.ncbi.nlm.nih.gov/pubmed/29795194
http://dx.doi.org/10.1038/s41467-018-04456-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966414/
https://www.ncbi.nlm.nih.gov/pubmed/29795194
http://dx.doi.org/10.1038/s41467-018-04456-6

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