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Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons

Despite critical roles of the hypothalamic arcuate neurons in controlling the growth and energy homeostasis, the gene regulatory network directing their development remains unclear. Here we report that the transcription factors Dlx1/2 and Otp coordinate the balanced generation of the two functionall...

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Detalles Bibliográficos
Autores principales: Lee, Bora, Kim, Janghyun, An, Taekyeong, Kim, Sangsoo, Patel, Esha M., Raber, Jacob, Lee, Soo-Kyung, Lee, Seunghee, Lee, Jae W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966420/
https://www.ncbi.nlm.nih.gov/pubmed/29795232
http://dx.doi.org/10.1038/s41467-018-04377-4