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Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons
Despite critical roles of the hypothalamic arcuate neurons in controlling the growth and energy homeostasis, the gene regulatory network directing their development remains unclear. Here we report that the transcription factors Dlx1/2 and Otp coordinate the balanced generation of the two functionall...
Autores principales: | Lee, Bora, Kim, Janghyun, An, Taekyeong, Kim, Sangsoo, Patel, Esha M., Raber, Jacob, Lee, Soo-Kyung, Lee, Seunghee, Lee, Jae W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966420/ https://www.ncbi.nlm.nih.gov/pubmed/29795232 http://dx.doi.org/10.1038/s41467-018-04377-4 |
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