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Profiling human breast epithelial cells using single cell RNA sequencing identifies cell diversity

Breast cancer arises from breast epithelial cells that acquire genetic alterations leading to subsequent loss of tissue homeostasis. Several distinct epithelial subpopulations have been proposed, but complete understanding of the spectrum of heterogeneity and differentiation hierarchy in the human b...

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Detalles Bibliográficos
Autores principales: Nguyen, Quy H., Pervolarakis, Nicholas, Blake, Kerrigan, Ma, Dennis, Davis, Ryan Tevia, James, Nathan, Phung, Anh T., Willey, Elizabeth, Kumar, Raj, Jabart, Eric, Driver, Ian, Rock, Jason, Goga, Andrei, Khan, Seema A., Lawson, Devon A., Werb, Zena, Kessenbrock, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966421/
https://www.ncbi.nlm.nih.gov/pubmed/29795293
http://dx.doi.org/10.1038/s41467-018-04334-1