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Profiling human breast epithelial cells using single cell RNA sequencing identifies cell diversity
Breast cancer arises from breast epithelial cells that acquire genetic alterations leading to subsequent loss of tissue homeostasis. Several distinct epithelial subpopulations have been proposed, but complete understanding of the spectrum of heterogeneity and differentiation hierarchy in the human b...
Autores principales: | Nguyen, Quy H., Pervolarakis, Nicholas, Blake, Kerrigan, Ma, Dennis, Davis, Ryan Tevia, James, Nathan, Phung, Anh T., Willey, Elizabeth, Kumar, Raj, Jabart, Eric, Driver, Ian, Rock, Jason, Goga, Andrei, Khan, Seema A., Lawson, Devon A., Werb, Zena, Kessenbrock, Kai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966421/ https://www.ncbi.nlm.nih.gov/pubmed/29795293 http://dx.doi.org/10.1038/s41467-018-04334-1 |
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