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TGF-β concentrations and activity are down-regulated in the aqueous humor of patients with neovascular age-related macular degeneration

Controversy still exists regarding the role of the TGF-β in neovascular age-related macular degeneration (nAMD), a major cause of severe visual loss in the elderly in developed countries. Here, we measured the concentrations of active TGF-β1, TGF-β2, and TGF-β3 by ELISA in the aqueous humor of 20 pa...

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Detalles Bibliográficos
Autores principales: Tosi, Gian Marco, Neri, Giovanni, Caldi, Elena, Fusco, Fiorella, Bacci, Tommaso, Tarantello, Antonio, Nuti, Elisabetta, Marigliani, Davide, Baiocchi, Stefano, Traversi, Claudio, Barbarino, Marcella, Eandi, Chiara M., Parolini, Barbara, Mundo, Lucia, Santucci, Annalisa, Orlandini, Maurizio, Galvagni, Federico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966430/
https://www.ncbi.nlm.nih.gov/pubmed/29795291
http://dx.doi.org/10.1038/s41598-018-26442-0