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Affinity kinetics of leptin-reactive immunoglobulins are associated with plasma leptin and markers of obesity and diabetes

Obese subjects display elevated plasma levels of leptin reflecting the phenomenon of leptin resistance. Here, we aimed to determine whether leptin-reactive immunoglobulins (Ig) are present in obese and type 2 diabetes (T2D) patients and whether their plasma levels and affinity kinetics may correlate...

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Detalles Bibliográficos
Autores principales: Bouhajja, Houda, Bougacha-Elleuch, Noura, Lucas, Nicolas, Legrand, Romain, Marrakchi, Rim, Kaveri, Srini V., Jamoussi, Kamel, Ayadi, Hammadi, Abid, Mohamed, Mnif-Feki, Mouna, Fetissov, Sergueï O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966443/
https://www.ncbi.nlm.nih.gov/pubmed/29795184
http://dx.doi.org/10.1038/s41387-018-0044-y