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Critical role of OX40 in the expansion and survival of CD4 T-cell-derived double-negative T cells
CD4(+) T-cell-converted CD4(−)CD8(−) double negative (cDNT) have strong suppressive activity in the maintenance of immune tolerance, whereas IL-2 promotes cDNT proliferation and enhances cDNT resistance to apoptosis. However, the intrinsic mechanisms that regulate the survival of cDNT are still unkn...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966453/ https://www.ncbi.nlm.nih.gov/pubmed/29795285 http://dx.doi.org/10.1038/s41419-018-0659-x |