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Critical role of OX40 in the expansion and survival of CD4 T-cell-derived double-negative T cells

CD4(+) T-cell-converted CD4(−)CD8(−) double negative (cDNT) have strong suppressive activity in the maintenance of immune tolerance, whereas IL-2 promotes cDNT proliferation and enhances cDNT resistance to apoptosis. However, the intrinsic mechanisms that regulate the survival of cDNT are still unkn...

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Detalles Bibliográficos
Autores principales:	Sun, Guangyong, Sun, Xiaojing, Li, Wei, Liu, Kai, Tian, Dan, Dong, Yiran, Sun, Xuelian, Xu, Hufeng, Zhang, Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966453/ https://www.ncbi.nlm.nih.gov/pubmed/29795285 http://dx.doi.org/10.1038/s41419-018-0659-x

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