Impact of the griffithsin anti-HIV microbicide and placebo gels on the rectal mucosal proteome and microbiome in non-human primates

Topical microbicides are being explored as an HIV prevention method for individuals who practice receptive anal intercourse. In vivo studies of these microbicides are critical to confirm safety. Here, we evaluated the impact of a rectal microbicide containing the antiviral lectin, Griffithsin (GRFT)...

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Detalles Bibliográficos
Autores principales: Girard, Lauren, Birse, Kenzie, Holm, Johanna B., Gajer, Pawel, Humphrys, Mike S., Garber, David, Guenthner, Patricia, Noël-Romas, Laura, Abou, Max, McCorrister, Stuart, Westmacott, Garrett, Wang, Lin, Rohan, Lisa C., Matoba, Nobuyuki, McNicholl, Janet, Palmer, Kenneth E., Ravel, Jacques, Burgener, Adam D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966460/
https://www.ncbi.nlm.nih.gov/pubmed/29795295
http://dx.doi.org/10.1038/s41598-018-26313-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966460/
https://www.ncbi.nlm.nih.gov/pubmed/29795295
http://dx.doi.org/10.1038/s41598-018-26313-8

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