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Carnitine palmitoyltransferase gene upregulation by linoleic acid induces CD4(+) T cell apoptosis promoting HCC development

Hepatocellular carcinoma (HCC) is a common cause of cancer-related death worldwide. As obesity and diabetes become more prevalent, the contribution of non-alcoholic fatty liver disease (NAFLD) to HCC is rising. Recently, we reported intrahepatic CD4(+) T cells are critical for anti-tumor surveillanc...

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Detalles Bibliográficos
Autores principales: Brown, Zachary J., Fu, Qiong, Ma, Chi, Kruhlak, Michael, Zhang, Haibo, Luo, Ji, Heinrich, Bernd, Yu, Su Jong, Zhang, Qianfei, Wilson, Andrew, Shi, Zhen-Dan, Swenson, Rolf, Greten, Tim F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966464/
https://www.ncbi.nlm.nih.gov/pubmed/29795111
http://dx.doi.org/10.1038/s41419-018-0687-6