Inducible Knockout of the Cyclin-Dependent Kinase 5 Activator p35 Alters Hippocampal Spatial Coding and Neuronal Excitability

p35 is an activating co-factor of Cyclin-dependent kinase 5 (Cdk5), a protein whose dysfunction has been implicated in a wide-range of neurological disorders including cognitive impairment and disease. Inducible deletion of the p35 gene in adult mice results in profound deficits in hippocampal-depen...

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Detalles Bibliográficos
Autores principales: Kamiki, Eriko, Boehringer, Roman, Polygalov, Denis, Ohshima, Toshio, McHugh, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966581/
https://www.ncbi.nlm.nih.gov/pubmed/29867369
http://dx.doi.org/10.3389/fncel.2018.00138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966581/
https://www.ncbi.nlm.nih.gov/pubmed/29867369
http://dx.doi.org/10.3389/fncel.2018.00138

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