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Inducible Knockout of the Cyclin-Dependent Kinase 5 Activator p35 Alters Hippocampal Spatial Coding and Neuronal Excitability

p35 is an activating co-factor of Cyclin-dependent kinase 5 (Cdk5), a protein whose dysfunction has been implicated in a wide-range of neurological disorders including cognitive impairment and disease. Inducible deletion of the p35 gene in adult mice results in profound deficits in hippocampal-depen...

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Detalles Bibliográficos
Autores principales:	Kamiki, Eriko, Boehringer, Roman, Polygalov, Denis, Ohshima, Toshio, McHugh, Thomas J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966581/ https://www.ncbi.nlm.nih.gov/pubmed/29867369 http://dx.doi.org/10.3389/fncel.2018.00138

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