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Suspected Lonely Mouse Syndrome as a Cage Effect in a Drug Safety Study

Studies have demonstrated that buprenorphine, a front line drug for veterinary analgesia, may alleviate symptoms of chronic pain. A cage side observation protocol was used to record behavioral signs in a mouse clinical trial of extended release buprenorphine. A retrospective review of the observatio...

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Detalles Bibliográficos
Autores principales: Ye, Xiaobu, Itzoe, MariaLisa, Sarabia-Estrada, Rachel, DeTolla, Louis, Tyler, Betty M., Guarnieri, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966667/
https://www.ncbi.nlm.nih.gov/pubmed/29854826
http://dx.doi.org/10.1155/2018/9562803