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Suspected Lonely Mouse Syndrome as a Cage Effect in a Drug Safety Study
Studies have demonstrated that buprenorphine, a front line drug for veterinary analgesia, may alleviate symptoms of chronic pain. A cage side observation protocol was used to record behavioral signs in a mouse clinical trial of extended release buprenorphine. A retrospective review of the observatio...
Autores principales: | Ye, Xiaobu, Itzoe, MariaLisa, Sarabia-Estrada, Rachel, DeTolla, Louis, Tyler, Betty M., Guarnieri, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966667/ https://www.ncbi.nlm.nih.gov/pubmed/29854826 http://dx.doi.org/10.1155/2018/9562803 |
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