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The role of mutated SOD1 gene in synaptic stripping and MHC class I expression following nerve axotomy in ALS murine model

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by motoneuron death. Several cellular pathways have been described to be involved in ALS pathogenesis; however, the involvement of presynaptic stripping and the related MHC class I molecules in mutant SOD1 m...

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Detalles Bibliográficos
Autores principales: Kassa, Roman M., Bonafede, Roberta, Boschi, Federico, Malatesta, Manuela, Mariotti, Raffaella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5966710/
https://www.ncbi.nlm.nih.gov/pubmed/29943955
http://dx.doi.org/10.4081/ejh.2018.2904