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The PDGFRβ/ERK1/2 pathway regulates CDCP1 expression in triple-negative breast cancer
BACKGROUND: CDCP1, a transmembrane protein with tumor pro-metastatic activity, was recently identified as a prognostic marker in TNBC, the most aggressive breast cancer subtype still lacking an effective molecular targeted therapy. The mechanisms driving CDCP1 over-expression are not fully understoo...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967041/ https://www.ncbi.nlm.nih.gov/pubmed/29792166 http://dx.doi.org/10.1186/s12885-018-4500-9 |