The PDGFRβ/ERK1/2 pathway regulates CDCP1 expression in triple-negative breast cancer

BACKGROUND: CDCP1, a transmembrane protein with tumor pro-metastatic activity, was recently identified as a prognostic marker in TNBC, the most aggressive breast cancer subtype still lacking an effective molecular targeted therapy. The mechanisms driving CDCP1 over-expression are not fully understoo...

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Detalles Bibliográficos
Autores principales: Forte, Luca, Turdo, Federica, Ghirelli, Cristina, Aiello, Piera, Casalini, Patrizia, Iorio, Marilena Valeria, D’Ippolito, Elvira, Gasparini, Patrizia, Agresti, Roberto, Belmonte, Beatrice, Sozzi, Gabriella, Sfondrini, Lucia, Tagliabue, Elda, Campiglio, Manuela, Bianchi, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967041/
https://www.ncbi.nlm.nih.gov/pubmed/29792166
http://dx.doi.org/10.1186/s12885-018-4500-9

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