Cargando…

Perinatal Pb(2+) exposure alters the expression of genes related to the neurodevelopmental GABA-shift in postnatal rats

BACKGROUND: Lead (Pb(2+)) is an environmental neurotoxicant that disrupts neurodevelopment, communication, and organization through competition with Ca(2+) signaling. How perinatal Pb(2+) exposure affects Ca(2+)-related gene regulation remains unclear. However, Ca(2+) activates the L-Type voltage se...

Descripción completa

Detalles Bibliográficos
Autores principales: Neuwirth, Lorenz S., Phillips, Greg R., El Idrissi, Abdeslem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967126/
https://www.ncbi.nlm.nih.gov/pubmed/29793500
http://dx.doi.org/10.1186/s12929-018-0450-4