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Perinatal Pb(2+) exposure alters the expression of genes related to the neurodevelopmental GABA-shift in postnatal rats
BACKGROUND: Lead (Pb(2+)) is an environmental neurotoxicant that disrupts neurodevelopment, communication, and organization through competition with Ca(2+) signaling. How perinatal Pb(2+) exposure affects Ca(2+)-related gene regulation remains unclear. However, Ca(2+) activates the L-Type voltage se...
Autores principales: | Neuwirth, Lorenz S., Phillips, Greg R., El Idrissi, Abdeslem |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967126/ https://www.ncbi.nlm.nih.gov/pubmed/29793500 http://dx.doi.org/10.1186/s12929-018-0450-4 |
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