Bulleyaconitine A attenuates hyperexcitability of dorsal root ganglion neurons induced by spared nerve injury: The role of preferably blocking Nav1.7 and Nav1.3 channels

BACKGROUND: Oral administration of Bulleyaconitine A, an extracted diterpenoid alkaloid from Aconitum bulleyanum plants, is effective for treating chronic pain in rats and in human patients, but the underlying mechanisms are poorly understood. RESULTS: As the hyperexcitability of dorsal root ganglio...

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Detalles Bibliográficos
Autores principales: Xie, Man-Xiu, Yang, Jie, Pang, Rui-Ping, Zeng, Wei-An, Ouyang, Han-Dong, Liu, Yan-Qing, Liu, Xian-Guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967161/
https://www.ncbi.nlm.nih.gov/pubmed/29783906
http://dx.doi.org/10.1177/1744806918778491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967161/
https://www.ncbi.nlm.nih.gov/pubmed/29783906
http://dx.doi.org/10.1177/1744806918778491

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