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Bulleyaconitine A attenuates hyperexcitability of dorsal root ganglion neurons induced by spared nerve injury: The role of preferably blocking Nav1.7 and Nav1.3 channels
BACKGROUND: Oral administration of Bulleyaconitine A, an extracted diterpenoid alkaloid from Aconitum bulleyanum plants, is effective for treating chronic pain in rats and in human patients, but the underlying mechanisms are poorly understood. RESULTS: As the hyperexcitability of dorsal root ganglio...
Autores principales: | Xie, Man-Xiu, Yang, Jie, Pang, Rui-Ping, Zeng, Wei-An, Ouyang, Han-Dong, Liu, Yan-Qing, Liu, Xian-Guo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967161/ https://www.ncbi.nlm.nih.gov/pubmed/29783906 http://dx.doi.org/10.1177/1744806918778491 |
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