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Synthesis of E- and Z-trisubstituted alkenes by catalytic cross-metathesis

Catalytic cross-metathesis is a central transformation in chemistry, and yet, corresponding methods for stereoselectively generating acyclic trisubstituted alkenes in either isomeric form do not exist. The key problems are lack of chemoselectivity, namely, the preponderance of side reactions involvi...

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Detalles Bibliográficos
Autores principales: Nguyen, Thach T., Koh, Ming Joo, Mann, Tyler J., Schrock, Richard R., Hoveyda, Amir H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967255/
https://www.ncbi.nlm.nih.gov/pubmed/29293209
http://dx.doi.org/10.1038/nature25002