Oxygen and Pt(II) self-generating conjugate for synergistic photo-chemo therapy of hypoxic tumor

Cancer cells in hypoxic tumors are remarkably resistant to photodynamic therapy. Here, we hypothesize that an oxygen and Pt(II) self-generating multifunctional nanocomposite could reverse the hypoxia-triggered PDT resistance. The nanocomposite contains Pt(IV) and chlorin e6, in which upconversion na...

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Detalles Bibliográficos
Autores principales: Xu, Shuting, Zhu, Xinyuan, Zhang, Chuan, Huang, Wei, Zhou, Yongfeng, Yan, Deyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967320/
https://www.ncbi.nlm.nih.gov/pubmed/29795534
http://dx.doi.org/10.1038/s41467-018-04318-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967320/
https://www.ncbi.nlm.nih.gov/pubmed/29795534
http://dx.doi.org/10.1038/s41467-018-04318-1

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