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Oxygen and Pt(II) self-generating conjugate for synergistic photo-chemo therapy of hypoxic tumor
Cancer cells in hypoxic tumors are remarkably resistant to photodynamic therapy. Here, we hypothesize that an oxygen and Pt(II) self-generating multifunctional nanocomposite could reverse the hypoxia-triggered PDT resistance. The nanocomposite contains Pt(IV) and chlorin e6, in which upconversion na...
Autores principales: | Xu, Shuting, Zhu, Xinyuan, Zhang, Chuan, Huang, Wei, Zhou, Yongfeng, Yan, Deyue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967320/ https://www.ncbi.nlm.nih.gov/pubmed/29795534 http://dx.doi.org/10.1038/s41467-018-04318-1 |
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