OGG1-initiated base excision repair exacerbates oxidative stress-induced parthanatos

Oxidative stress-induced DNA damage has been well acknowledged as a major cause leading to cell death, which is etiologically linked to ischemic injury and degenerative alterations. The most common oxidation product of DNA is base lesion 8-oxo-7,8-dihydroguanine (8-oxoG), which is repaired by 8-oxoG...

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Detalles Bibliográficos
Autores principales: Wang, Ruoxi, Li, Chunshuang, Qiao, Ping, Xue, Yaoyao, Zheng, Xu, Chen, Hongyu, Zeng, Xianlu, Liu, Wenguang, Boldogh, Istvan, Ba, Xueqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967321/
https://www.ncbi.nlm.nih.gov/pubmed/29795387
http://dx.doi.org/10.1038/s41419-018-0680-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967321/
https://www.ncbi.nlm.nih.gov/pubmed/29795387
http://dx.doi.org/10.1038/s41419-018-0680-0

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