ATG5 overexpression is neuroprotective and attenuates cytoskeletal and vesicle-trafficking alterations in axotomized motoneurons

Injured neurons should engage endogenous mechanisms of self-protection to limit neurodegeneration. Enhancing efficacy of these mechanisms or correcting dysfunctional pathways may be a successful strategy for inducing neuroprotection. Spinal motoneurons retrogradely degenerate after proximal axotomy...

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Detalles Bibliográficos
Autores principales: Leiva-Rodríguez, Tatiana, Romeo-Guitart, David, Marmolejo-Martínez-Artesero, Sara, Herrando-Grabulosa, Mireia, Bosch, Assumpció, Forés, Joaquim, Casas, Caty
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967323/
https://www.ncbi.nlm.nih.gov/pubmed/29799519
http://dx.doi.org/10.1038/s41419-018-0682-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967323/
https://www.ncbi.nlm.nih.gov/pubmed/29799519
http://dx.doi.org/10.1038/s41419-018-0682-y

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