Heat shock factor 1 confers resistance to lapatinib in ERBB2-positive breast cancer cells

Despite success of ERBB2-targeted therapies such as lapatinib, resistance remains a major clinical concern. Multiple compensatory receptor tyrosine kinase (RTK) pathways are known to contribute to lapatinib resistance. The heterogeneity of these adaptive responses is a significant hurdle for finding...

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Detalles Bibliográficos
Autores principales: Yallowitz, Alisha, Ghaleb, Amr, Garcia, Lucas, Alexandrova, Evguenia M., Marchenko, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967334/
https://www.ncbi.nlm.nih.gov/pubmed/29799521
http://dx.doi.org/10.1038/s41419-018-0691-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967334/
https://www.ncbi.nlm.nih.gov/pubmed/29799521
http://dx.doi.org/10.1038/s41419-018-0691-x

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