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Gamma synuclein is a novel Twist1 target that promotes TGF-β-induced cancer cell migration and invasion

Transforming growth factor β (TGF-β) is critical for embryonic development, adult tissue homeostasis, and tumor progression. TGF-β suppresses tumors at early stage, but promotes metastasis at later stage through oncogenes such as Twist1. Gamma-synuclein (SNCG) is overexpressed in a variety of invasi...

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Detalles Bibliográficos
Autores principales: Shao, Ting, Song, Peiying, Hua, Hui, Zhang, Hongying, Sun, Xiangmin, Kong, Qingbin, Wang, Jiao, Luo, Ting, Jiang, Yangfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967338/
https://www.ncbi.nlm.nih.gov/pubmed/29795373
http://dx.doi.org/10.1038/s41419-018-0657-z