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Rhodopsin-cyclases for photocontrol of cGMP/cAMP and 2.3 Å structure of the adenylyl cyclase domain

The cyclic nucleotides cAMP and cGMP are important second messengers that orchestrate fundamental cellular responses. Here, we present the characterization of the rhodopsin-guanylyl cyclase from Catenaria anguillulae (CaRhGC), which produces cGMP in response to green light with a light to dark activ...

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Detalles Bibliográficos
Autores principales: Scheib, Ulrike, Broser, Matthias, Constantin, Oana M., Yang, Shang, Gao, Shiqiang, Mukherjee, Shatanik, Stehfest, Katja, Nagel, Georg, Gee, Christine E., Hegemann, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967339/
https://www.ncbi.nlm.nih.gov/pubmed/29799525
http://dx.doi.org/10.1038/s41467-018-04428-w