Cargando…

Rhodopsin-cyclases for photocontrol of cGMP/cAMP and 2.3 Å structure of the adenylyl cyclase domain

The cyclic nucleotides cAMP and cGMP are important second messengers that orchestrate fundamental cellular responses. Here, we present the characterization of the rhodopsin-guanylyl cyclase from Catenaria anguillulae (CaRhGC), which produces cGMP in response to green light with a light to dark activ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Scheib, Ulrike, Broser, Matthias, Constantin, Oana M., Yang, Shang, Gao, Shiqiang, Mukherjee, Shatanik, Stehfest, Katja, Nagel, Georg, Gee, Christine E., Hegemann, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967339/ https://www.ncbi.nlm.nih.gov/pubmed/29799525 http://dx.doi.org/10.1038/s41467-018-04428-w

Ejemplares similares

The inner mechanics of rhodopsin guanylyl cyclase during cGMP-formation revealed by real-time FTIR spectroscopy
por: Fischer, Paul, et al.
Publicado: (2021)

Spatial resolution of cAMP signaling by soluble adenylyl cyclase
por: Caldieri, Giusi, et al.
Publicado: (2016)

Modulation of cGMP/cAMP crosstalk on the level of PDE3 in animals lacking NO-sensitive guanylyl cyclase
por: Friebe, Andreas, et al.
Publicado: (2015)

Absorption and Emission Spectroscopic Investigation of Thermal Dynamics and Photo-Dynamics of the Rhodopsin Domain of the Rhodopsin-Guanylyl Cyclase from the Nematophagous Fungus Catenaria anguillulae
por: Penzkofer, Alfons, et al.
Publicado: (2017)

Bicarbonate-responsive “soluble” adenylyl cyclase defines a nuclear cAMP microdomain
por: Zippin, Jonathan H., et al.
Publicado: (2004)

Far-Red Absorbing Rhodopsins, Insights From Heterodimeric Rhodopsin-Cyclases
por: Broser, Matthias
Publicado: (2022)

High adenylyl cyclase activity and in vivo cAMP fluctuations in corals suggest central physiological role
por: Barott, K. L., et al.
Publicado: (2013)

Photoactivated adenylyl cyclase (PAC) reveals novel mechanisms underlying cAMP-dependent axonal morphogenesis
por: Zhou, Zhiwen, et al.
Publicado: (2016)

Increased Levels of cAMP by the Calcium-Dependent Activation of Soluble Adenylyl Cyclase in Parkin-Mutant Fibroblasts
por: Tanzarella, Paola, et al.
Publicado: (2019)

Proteomic Analysis of the Role of the Adenylyl Cyclase–cAMP Pathway in Red Blood Cell Mechanical Responses
por: Ugurel, Elif, et al.
Publicado: (2022)

Distribution of adenylyl cyclase/cAMP phosphodiesterase gene, CAPE, in streptophytes reproducing via motile sperm
por: Yamamoto, Chiaki, et al.
Publicado: (2021)

Optogenetic manipulation of cGMP in cells and animals by the tightly light-regulated guanylyl-cyclase opsin CyclOp
por: Gao, Shiqiang, et al.
Publicado: (2015)

Plasticity and therapeutic potential of cAMP and cGMP-specific phosphodiesterases in Toxoplasma gondii
por: Vo, Kim Chi, et al.
Publicado: (2022)

Signaling via guanylyl cyclase C: cGMP, Src and p21
por: Basu, Nirmalya, et al.
Publicado: (2011)

Guanylate cyclase-C/cGMP: an emerging pathway in the regulation of visceral pain
por: Hannig, Gerhard, et al.
Publicado: (2014)

Identification of novel target proteins of cGMP/cAMP signaling pathway using cGMP/cAMP capture compound mass spectrometry (CCMS)
por: Luo, Yan, et al.
Publicado: (2009)

Adenylyl Cyclase α and cAMP Signaling Mediate Plasmodium Sporozoite Apical Regulated Exocytosis and Hepatocyte Infection
por: Ono, Takeshi, et al.
Publicado: (2008)

Soluble Adenylyl Cyclase Is Localized to Cilia and Contributes to Ciliary Beat Frequency Regulation via Production of cAMP
por: Schmid, Andreas, et al.
Publicado: (2007)

Differential regulation of Paramecium ciliary motility by cAMP and cGMP
Publicado: (1988)

Biophysical Techniques for Detection of cAMP and cGMP in Living Cells
por: Sprenger, Julia U., et al.
Publicado: (2013)

Role of an adenylyl cyclase isoform in ethanol's effect on cAMP regulated gene expression in NIH 3T3 cells
por: Hill, Rebecca A., et al.
Publicado: (2016)

Glucose and GLP-1 Stimulate cAMP Production via Distinct Adenylyl Cyclases in INS-1E Insulinoma Cells
por: Ramos, Lavoisier S., et al.
Publicado: (2008)

The Guanylate Cyclase C—cGMP Signaling Axis Opposes Intestinal Epithelial Injury and Neoplasia
por: Rappaport, Jeffrey A., et al.
Publicado: (2018)

Adenyl cyclases and cAMP in plant signaling - past and present
por: Gehring, Chris
Publicado: (2010)

IL-4 induces cAMP and cGMP in human monocytic cells
por: Dugas, B., et al.
Publicado: (1995)

Role of cGMP and cAMP in the hemodynamic response to intrathecal sildenafil administration
por: Bombarda, Gabriela, et al.
Publicado: (2011)

cGMP and cAMP differentially regulate differentiation and function of brown adipocytes
por: Jennissen, Katja, et al.
Publicado: (2011)

Regulation of cGMP levels by guanylate cyclase in truncated frog rod outer segments
Publicado: (1989)

PDGF regulates guanylate cyclase expression and cGMP signaling in vascular smooth muscle
por: Hildebrand, Staffan, et al.
Publicado: (2022)

Optogenetic manipulation of neuronal and cardiomyocyte functions in zebrafish using microbial rhodopsins and adenylyl cyclases
por: Hagio, Hanako, et al.
Publicado: (2023)

Homogeneous single-label cGMP detection platform for the functional study of nitric oxide-sensitive (soluble) guanylyl cyclases and cGMP-specific phosphodiesterases
por: Kopra, Kari, et al.
Publicado: (2020)

An Improved Targeted cAMP Sensor to Study the Regulation of Adenylyl Cyclase 8 by Ca(2+) Entry through Voltage-Gated Channels
por: Everett, Katy L., et al.
Publicado: (2013)

Hypoxia induces cancer-associated cAMP/PKA signalling through HIF-mediated transcriptional control of adenylyl cyclases VI and VII
por: Simko, Veronika, et al.
Publicado: (2017)

Effect of Soluble Adenylyl Cyclase (ADCY10) Inhibitors on the LH-Stimulated cAMP Synthesis in Mltc-1 Leydig Cell Line
por: Nguyen, Thi Mong Diep, et al.
Publicado: (2021)

Excitation, adaption, and deadaptation of the cAMP-mediated cGMP Response in dictyostelium discoideum
por: Van Haaster, PJM, et al.
Publicado: (1983)

Differential regulation of platelet inhibition by cGMP- and cAMP-dependent protein kinases
por: Subramanian, Hariharan, et al.
Publicado: (2013)

Intermingled cAMP, cGMP and calcium spatiotemporal dynamics in developing neuronal circuits
por: Averaimo, Stefania, et al.
Publicado: (2014)

Effects of carbon monoxide-releasing molecules on cGMP levels and soluble guanylate cyclase activity
por: Marazioti, Antonia, et al.
Publicado: (2009)

Blocking soluble guanylate cyclase could be the present and future of NO/cGMP inhibition for vasoplegia treatment
por: Barbosa Evora, Paulo Roberto
Publicado: (2018)

Particulate Guanylyl Cyclase A/cGMP Signaling Pathway in the Kidney: Physiologic and Therapeutic Indications
por: Chen, Yang, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_4qnt0je1jdis7du6gv5j6nufp7