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Estimation of the radiation-induced DNA double-strand breaks number by considering cell cycle and absorbed dose per cell nucleus

DNA double-strand breaks (DSBs) are thought to be the main cause of cell death after irradiation. In this study, we estimated the probability distribution of the number of DSBs per cell nucleus by considering the DNA amount in a cell nucleus (which depends on the cell cycle) and the statistical vari...

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Detalles Bibliográficos
Autores principales: Mori, Ryosuke, Matsuya, Yusuke, Yoshii, Yuji, Date, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967466/
https://www.ncbi.nlm.nih.gov/pubmed/29800455
http://dx.doi.org/10.1093/jrr/rrx097