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Repair kinetics of DNA double-strand breaks and incidence of apoptosis in mouse neural stem/progenitor cells and their differentiated neurons exposed to ionizing radiation
Neuronal loss leads to neurodegenerative disorders, including Alzheimer’s disease, Parkinson’s disease and Huntington’s disease. Because of their long lifespans, neurons are assumed to possess highly efficient DNA repair ability and to be able to protect themselves from deleterious DNA damage such a...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967548/ https://www.ncbi.nlm.nih.gov/pubmed/29351627 http://dx.doi.org/10.1093/jrr/rrx089 |