Repair kinetics of DNA double-strand breaks and incidence of apoptosis in mouse neural stem/progenitor cells and their differentiated neurons exposed to ionizing radiation

Neuronal loss leads to neurodegenerative disorders, including Alzheimer’s disease, Parkinson’s disease and Huntington’s disease. Because of their long lifespans, neurons are assumed to possess highly efficient DNA repair ability and to be able to protect themselves from deleterious DNA damage such a...

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Detalles Bibliográficos
Autores principales: Kashiwagi, Hiroki, Shiraishi, Kazunori, Sakaguchi, Kenta, Nakahama, Tomoya, Kodama, Seiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Regular Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967548/
https://www.ncbi.nlm.nih.gov/pubmed/29351627
http://dx.doi.org/10.1093/jrr/rrx089

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