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The combination of ionizing radiation and proteasomal inhibition by bortezomib enhances the expression of NKG2D ligands in multiple myeloma cells

Bortezomib, which is a potent proteasome inhibitor, has been used as a first-line drugs to treat multiple myeloma for a few decades, and radiotherapy has frequently been applied to manage acute bone lesions in the patients. Therefore, it was necessary to investigate what the benefits might be if the...

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Detalles Bibliográficos
Autores principales: Lee, Young Shin, Heo, Woong, Nam, Jiho, Jeung, Young Hwa, Bae, Jaeho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5967576/
https://www.ncbi.nlm.nih.gov/pubmed/29518205
http://dx.doi.org/10.1093/jrr/rry005